Semax 10mg

The neuropeptide analogue. BDNF modulation. Cognitive signalling at the synaptic level.

$ 79.99

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MOA

Overview

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10), modified to eliminate hormonal activity while preserving its central nervous system effects. Originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Semax has been extensively studied for its role in neuroprotection, cognitive enhancement, and brain-derived neurotrophic factor (BDNF) modulation. Unlike traditional stimulants, Semax does not act through direct neurotransmitter release. Instead, it influences gene expression and intracellular signalling pathways that regulate neuronal growth, adaptation, and resilience under stress conditions. Its mechanism positions it as a regulatory compound rather than an acute stimulant within cognitive research models.

What it does

Semax exerts its primary effects through upregulation of BDNF and other neurotrophins — proteins responsible for neuronal survival, synaptic plasticity, and long-term potentiation. Increased BDNF expression enhances the brain’s ability to form new neural connections, a process central to learning, memory consolidation, and adaptive cognitive function. It also modulates dopaminergic and serotonergic systems indirectly, improving signal efficiency without overstimulation. In ischemic and hypoxic research models, Semax has demonstrated neuroprotective effects by reducing oxidative stress, stabilizing neuronal membranes, and limiting excitotoxic damage. Additionally, Semax influences cerebral blood flow and metabolic activity in key brain regions, supporting improved oxygen and nutrient delivery under stress conditions. Its combined effects target both structural and functional aspects of cognitive performance.

Research areas

Neuroplasticity and synaptic adaptation · Cognitive performance and memory research · Ischemic brain injury and stroke models · Anxiety and stress-response modulation · Neuroprotection and oxidative stress research · Attention and executive function studies

Key facts

Form	Lyophilised powder — requires reconstitution with bacteriostatic water
Storage	Lyophilised: -20°C. Reconstituted: 2–8°C, use within 21 days
Purity	≥99% — third-party COA verified, batch-specific documentation included
Origin	Synthetic analogue of ACTH (4–10) fragment
Note	Non-hormonal derivative — no corticosteroid activity

For research use only. Not for human consumption. This product is not approved for human use by the FDA or any regulatory body.

More Information

All products offered on this website are intended solely for laboratory research and development purposes. They are not approved for human or veterinary use.

Statements on this site have not been evaluated by the U.S. Food and Drug Administration (FDA). Products are not intended to diagnose, treat, cure, mitigate, or prevent any disease.

Products are manufactured in U.S.-based facilities operating under applicable cGMP standards. This website does not operate as a compounding pharmacy under Section 503A of the Federal Food, Drug, and Cosmetic Act.

A valid health screening is required prior to order fulfillment. After checkout, you will receive instructions to complete the required intake process. Orders will be processed once the screening has been completed and approved. Each completed screening remains valid for 12 months.